The challenger has become the champion as Ippo Makunouchi now wears the featherweight championship belt of Japan.
Some time has passed since Ippo's victory, and he has found his friends and coach as supportive as ever; his crush, Kumi Mashiba, seems to enjoy spending time with him as well. Things are looking bright for the new champion, but just as he once set his sights on becoming the best, his first challenger poses an intimidating threat.
Kazuki Sanada works as a doctor at the same hospital as Kumi and fights strategically. Known for integrating his knowledge of the human body into his fights, Sanada is a fearsome contender—however, more unnerving than his physical ability, he has garnered the support of the nurses. Despite being the champion, Ippo feels the pressure as he must face the daunting challenge, retain his belt, and win over the girl he loves.
[Written by MAL Rewrite]+ More
Characters & Voice Actors

Aoki, Masaru
Supporting
Commentator
Supporting
Fujii, Minoru
Supporting
Iimura, Mari
Supporting
Kimura, Tatsuya
SupportingRecommended for you
Bikini Warriors
TV
4m
Majo demo Steady
OVA
41m
Aooni The Blue Monster
TV
3m
Harmagedon
Movie
131m
The Cosmopolitan Prayers
TV
8m
The Blossom Man
Movie
6m
Saishuu Shiken Kujira
ONA
5m
Voltage Fighter Gowcaizer: The Movie
Movie
90m
My Sister, My Writer
TV
23m
Debutante Detective Corps
OVA
30m
Pants no Ana: Mambo de Ganbo!
OVA
32m
Ame-iro Cocoa: Side G
TV
2m
Chargeman Ken!
TV
6m
Ame-Con!!
TV
2m
Art of Fighting
OVA
49m